# Syed Mian Source: https://hello.cv/syedmian ## Work ### Senior Research Fellow | The Francis Crick Institute ### Visiting Lecturer | University of Roehampton ### King's College London ### Post Doc Research Associate | King's College London ## Education ### King's College London | PhD ### University of Greenwich | BSc (H) ## Publications ### Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1 -mutated myelodysplasia Science Translational Medicine journal-article ### Single cell analyses identify a highly regenerative and homogenous human CD34+ hematopoietic stem cell population Nature Communications journal-article ### Nature or Nurture? Role of the Bone Marrow Microenvironment in the Genesis and Maintenance of Myelodysplastic Syndromes Cancers journal-article ### Nature or Nurture? Role of the Bone Marrow Microenvironment in the Genesis and Maintenance of Myelodysplastic Syndromes Cancers journal-article ### Ectopic Humanized Mesenchymal Niche in Mice Enables Robust Engraftment of Myelodysplastic Stem Cells Cancer discovery journal-article ### Engraftment of Hematopoietic Cells in Biomaterials Implanted in Immunodeficient Models Methods in Molecular Biology book-chapter ### Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction Blood journal-article ### Treg sensitivity to FasL and relative IL-2 deprivation drive Idiopathic Aplastic Anemia immune dysfunction Blood journal-article ### Impact of somatic mutations in myelodysplastic patients with isolated partial or total loss of chromosome 7 Leukemia journal-article ### Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Blood Cancer Discovery journal-article ### Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells Blood Cancer Discovery journal-article ### Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study journal-article ### Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia The Lancet Haematology journal-article ### Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches The Journal of Experimental Medicine journal-article ### Modeling the human bone marrow niche in mice The Journal of experimental medicine journal-article ### Preclinical modeling of myelodysplastic syndromes Leukemia journal-article ### Bone Marrow Stem Cells from Patients with Myelodysplastic Syndrome (MDS) Engraft and Migrate in-between the Humanized Niches in Immuno-Compromised Mouse Models Blood other ### Preclinical modeling of myelodysplastic syndromes Experimental Hematology journal-article ### Preclinical modeling of myelodysplastic syndromes Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K journal-article ### Versatile humanized niche model enables study of normal and malignant human hematopoiesis Journal of Clinical Investigation journal-article ### Versatile humanized niche model enables study of normal and malignant human hematopoiesis Journal of Clinical Investigation journal-article ### Myelodysplastic syndrome can propagate from the multipotent progenitor compartment Haematologica journal-article ### Functional Characteristics of FAS-L Resistant and IL-2 Deprived Regulatory T Cells (Treg A) in Idiopathic Aplastic Anaemia Blood journal-article ### Deep-phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment Blood journal-article ### Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment Blood journal-article ### High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS) Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K journal-article ### CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome: a retrospective mutational analysis The Lancet Haematology journal-article ### CSNK1A1 mutations and isolated del(5q) abnormality in myelodysplastic syndrome The Lancet Haematology journal-article ### SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment Nature Communications journal-article ### SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment Nat Comms journal-article ### High concordance of genomic and cytogenetic aberrations between peripheral blood and bone marrow in myelodysplastic syndrome (MDS) Leukemia journal-article ### Somatic mutations identify a subgroup of aplastic anemia patients who progress to myelodysplastic syndrome Blood journal-article ### Somatic mutations identify a sub-group of aplastic anemia patients that progress to myelodysplastic syndrome Blood journal-article ### Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome Haematologica journal-article ### Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome Blood journal-article ### Utility of peripheral blood for cytogenetic and mutation analysis in myelodysplastic syndrome Blood journal-article ### TP53mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis British Journal of Haematology journal-article ### TP53 mutations in myelodysplastic syndrome are strongly correlated with aberrations of chromosome 5, and correlate with adverse prognosis British Journal of Haematology journal-article ### Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome Haematologica journal-article ### Functional characterization of CD4(+) T cells in aplastic anemia Blood journal-article ### Correction: B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease PLoS ONE journal-article ### B-RAF Mutant Alleles Associated with Langerhans Cell Histiocytosis, a Granulomatous Pediatric Disease PL o S One journal-article ### Functional characterization of CD4+ T cells in aplastic anemia Blood journal-article ### Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value Blood journal-article ### Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value Blood journal-article ### Novel TET2 Mutations Associated With UPD4q24 in Myelodysplastic Syndrome Journal of Clinical Oncology journal-article ### Novel TET2 mutations associated with UPD4q24 in myelodysplastic syndrome Journal of Clinical Oncology journal-article ## Source Read this profile on Hello.cv: https://hello.cv/syedmian Create your free profile at https://hello.cv